Here are the latest developments:

- Israel responds to latest missile strikes -

Just after midnight local time Tuesday, Israel's military said it was working to intercept a large wave of missiles launched from Iran targeting multiple locations, including Jerusalem.

"A short while ago, the IDF identified missiles launched from Iran toward the territory of the State of Israel. Defensive systems are operating to intercept the threat," the military said.

- US warns citizens in Middle East to 'depart now' -

The US State Department urged Americans to leave much of the Middle East, including Egypt and Gulf states, due to the US-Israeli war on Iran.

The State Department "urges Americans to DEPART NOW from the countries below using available commercial transportation, due to serious safety risks," wrote Mora Namdar, the assistant secretary of state for consular affairs, in a social media post.

The 14 countries included in the warning were Bahrain, Egypt, Iran, Iraq, Israel and the Palestinian territories, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, the United Arab Emirates and Yemen.

- Iran state broadcaster headquarters 'struck and dismantled' -

Israel's military claimed it had "struck and dismantled" the headquarters of Iran's state radio and television broadcaster, the Islamic Republic of Iran Broadcasting (IRIB), saying it had "called for the destruction of the State of Israel and for the use of nuclear weapons."

"A short while ago, the Israeli Air Force struck and dismantled the Iranian terrorist regime's communications centre" in Tehran, the military said, referring to IRIB.

- Iran 'will burn any ship' passing through Hormuz -

A general in Iran's Revolutionary Guards threatened to "burn any ship" seeking to navigate the Strait of Hormuz, a vital route for oil and gas shipments.

"We will also attack oil pipelines and will not allow a single drop of oil to leave the region. Oil price will reach $200 in the coming days," General Sardar Jabbari said in a post on the Guards' Telegram channel.

- Israel was about to strike Iran, says Rubio -

The United States attacked Iran after learning that ally Israel was going to strike, which would have meant retaliation against US forces, Secretary of State Marco Rubio said.

"We knew that if we didn't preemptively go after them before they launched those attacks, we would suffer higher casualties," Rubio told reporters.

- UNESCO palace in Tehran damaged -

Iran's UNESCO-listed Golestan Palace in Tehran has been damaged in US and Israeli strikes, local media reported.

"Following the joint US-Israeli attack on Arag square in southern Tehran on Sunday evening, parts of the Golestan Palace... were damaged," the ISNA news agency reported, adding that windows, doors, and mirrors were hit by reverberations from blasts.

- US says hit 1,250 targets so far -

The United States hit more than 1,250 targets in the first 48 hours of the war against Iran, the US military said.

Targets struck included command-and-control centers, ballistic missile sites, Iranian navy ships and submarines, and anti-ship missile sites, according to a fact sheet released by the US Central Command, which is responsible for American forces in the region.

- Qatar downs Iran jets -

Qatar downed two Iranian bombers and halted LNG production, as Tehran widened its attacks to hit oil facilities in Saudi Arabia and the UAE in a sharply escalating Gulf crisis that has sent prices soaring.

Qatar's air force shot down two Sukhoi Su-24 bombers, the defense ministry said -- the first time a Gulf country has hit Iranian planes, after Tehran began region-wide attacks in retaliation for US and Israeli strikes that have devastated its leadership.

- Trump warns of longer war -

Trump signaled that US strikes on Iran could go much longer than originally predicted, as his administration sought to counter criticism about conflicting messages on the war's goals.

In his first public comments since launching the military operation, the president laid out what he said were four key objectives for hitting Iran.

"First, we're destroying Iran's missile capabilities...Second, we're annihilating their navy...Third, we're ensuring that the world's number-one sponsor of terror can never obtain a nuclear weapon.

"Finally we are ensuring the Iranian regime can't continue to arm, fund and direct terrorist armies outside of their borders."

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Daily Mail

A.P. MOELLER-MAERSK