Authorities reported that falling munitions had hit multiple sites in central Israel in the overnight barrage that triggered air raid sirens across the area, after another day of heavy Israeli bombardments in Iran and Lebanon.

The latest deaths took the toll from missile attacks on Israel since the start of the Middle East war late last month to 14 people.

AFP footage from Ramat Gan, a city just outside Tel Aviv, showed police officers, rescuers and military personnel on a street strewn with rubble.

Israel's Magen David Adom emergency medical service said two people were found dead at the scene.

"We saw smoke rising from a building with extensive damage and shattered glass," said a statement from the medics.

In Bnei Brak, another city in the Tel Aviv area, a man was lightly injured by shrapnel, the medical service said.

Images shared by Magen David Adom showed destruction in multiple locations, including cars on fire, destroyed vehicles and rubble.

Israel's police said its bomb disposal experts were "operating at several impact sites involving munition debris within the (Tel Aviv) district".

The national railway company said in a statement posted online that shrapnel caused damage to platforms at Tel Aviv's main station, announcing that trains were "temporarily suspended across the country".

It said no casualties were reported.

The military shared footage of Home Front Command teams at a train station, showing shattered glass at a platform and some damage to train windows.

In a separate statement, the Home Front Command said its search and rescue teams were "operating at several sites in central Israel where reports of impacts have been received".

Iran's Revolutionary Guards said in a statement they had launched missiles at central Israel "in revenge for the blood of martyr Dr Ali Larijani and his companions".

Israel said on Tuesday it had killed Larijani, Iran's security chief, and Tehran has since confirmed his death.