"Initial investigations indicate that some military locations in Isfahan were targeted," the Fars news agency quoted Akbar Salehi, a security official at the governor's office in Isfahan province, as saying.

The official also said the extent of the damage and any casualties were not immediately clear.

Isfahan province is a key hub for Iran's defence industry and hosts major nuclear facilities, including Natanz.

The nuclear sites were targeted during a 12-day conflict with Israel last June, as well as in the current war that began on February 28, according to Iranian officials.

The province is home to several major military bases, including the Badr airbase, the 8th Shekari airbase, and the 4th Air Force base.

Strikes during the conflict have also hit civilian and historical infrastructure, including the Isfahan University of Technology.

Several heritage sites listed by UNESCO have been reported damaged in Isfahan's Naqsh-e Jahan Square, including the Safavid-era Abbasi Jameh Mosque and Ali Qapu Palace.

On Tuesday, Hassan Fartousi, secretary-general of the Iranian National Commission for UNESCO, said in a press conference that damage in the province was "huge".

Industrial facilities were also affected, with strikes hitting the Mobarakeh Steel Company complex.