A Huthi statement cited "US-British aggression" for the new attack, as witnesses also reported the blast.
There was no immediate comment from Israel, the United States or Britain.
"I heard the blast. My house shook," one resident of the rebel-held capital Sanaa told AFP.
The attack followed Thursday's Israeli raids on infrastructure including Sanaa's international airport that left six people dead.
The strikes came in response to a series of Huthi attacks on Israel.
The rebels have also been firing on the Red Sea and Gulf of Aden shipping route for months, prompting a series of reprisal strikes by US and British forces.
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