Trump has warned that unless Tehran allows free passage through the strategic oil chokepoint the Strait of Hormuz by midnight GMT, the United States will unleash what he called the "complete demolition" of Iran's critical infrastructure.

"We hope that the countries in the region will use all their diplomatic and political capabilities to prevent such a tragedy from befalling the region," Mohammad Toutounji told AFP.

During more than a month of war, Iran has responded to US and Israeli strikes that decapitated its leadership by launching drone and missile attacks across the Gulf.

Iran has targeted US embassies, bases and assets but also airports, major oil and gas infrastructure as well as landmarks, ports, hotels and residential areas.

But Toutounji said Tehran "does not want to escalate tensions in the region".

"On the contrary, it consistently strives to de-escalate tensions and diligently and in good faith follows the efforts and initiatives of other countries in this regard," he said.

He warned that US strikes on vital facilities would lead to "complete and total cessation of energy exports from the region".

Earlier on Tuesday, Iran's ambassador to Pakistan, which is mediating between Iran and the United States, said on X that efforts to end the war were approaching a "critical" stage.

"Positive and productive endeavours in Good Will and Good Office to stop the war is approaching a critical, sensitive stage," Reza Amiri Moghadam wrote on X, without giving details.