Blinken made the comments in Jerusalem alongside his Israeli counterpart Yair Lapid, who told reporters Israel had "disagreements" with Washington about a possible deal to revive the 2015 nuclear accord with Tehran.

Blinken said President Joe Biden's administration believes that "the return to full implementation" of the deal was "the best way to put Iran's programme back in the box that it was in but has escaped from since the United States withdrew from the agreement," under former president Donald Trump in 2018.

Israel's government firmly opposed the terms of the 2015 deal and has said that re-activating the original deal is insufficient to curb the Iranian threat.

But, Blinken said, "when it comes to the most important element, (Israel and the US) see eye to eye. We are both committed, both determined, that Iran will never acquire a nuclear weapon."

Lapid said that amid its differences with Washington, Israel remains in "open and honest dialogue" with its closest ally on the Iran nuclear issue.

"Israel will do anything we believe is needed to stop the Iranian nuclear program. Anything. From our point of view, the Iranian threat is not theoretical. The Iranians want to destroy Israel. They will not succeed. We will not let them," Lapid said.

The European Union's foreign policy chief said at the weekend that a deal with Iran, known as the Joint Collective Plan of Action, will likely be renewed "in a matter of days."

Iran has been engaged for months in talks in Vienna to revive the accord with Britain, China, France, Germany and Russia directly. The United States is taking part indirectly in the negotiations.