"During the recent missile salvo fired from Iran toward Jerusalem, several intercepts occurred over the city," the police said.

Following the interceptions, police located "fragments of missiles and interceptor debris, some of significant size, at multiple sites in the Old City, including the Temple Mount complex, the Church of the Holy Sepulchre complex, and the Jewish Quarter", they added.

The force shared photos showing debris on a roof near the Holy Sepulchre church, a cordon set up in the Al-Aqsa mosque compound and the smashed windscreen of a car.

"This incident underscores that the enemy does not distinguish between religions or places of worship -- synagogues, mosques, or churches," the police statement said.

The Old City is located in east Jerusalem, which Israel occupied in 1967 and later annexed in a move that is not internationally recognised.

It houses the Al-Aqsa mosque, Islam's third holiest site; the Church of the Holy Sepulchre, where Christians hold that Christ was crucified, entombed and resurrected; and the Western Wall, considered the holiest site where Jews are allowed to pray.

AFP journalists also saw missile debris that had hit the roof of a residential building in east Jerusalem.

A cylinder about one metre in diameter and several metres long protruded from the tiled roof of the three-story building as first responders inspected the damage.

No injuries or deaths were reported in Jerusalem.