A spokesperson for Israel's Magen David Adom emergency medical service said paramedics were providing medical treatment to "six people who were lightly injured by blast effects", updating an earlier toll of two injured.

Earlier on Thursday, a spokesperson for MDA told public radio there was damage to several houses in the central city of Kafr Qassem, whose Mayor Haitham Taha said it was caused by cluster munitions.

The military said Home Front Command rescuers were called to an impact site "in central Israel".

In three separate statements in around 90 minutes, the military said it had "identified missiles launched from Iran toward the territory of the State of Israel".

"Defensive systems are operating to intercept the threat," the statements said, followed by announcements that people were "now permitted to leave protected spaces in all areas of the country".

Air raid sirens wailed across central Israel, including in Jerusalem and Israeli settlements in the occupied West Bank, while blasts were heard in Tel Aviv after the latest warning.

The attacks came more than 14 hours after the military last announced incoming missiles from Iran.

Central Israel came under fire overnight from Lebanon, where Iran-backed militant group Hezbollah claimed a series of attacks targeting military sites. Israeli media said six rockets were intercepted.