"There are six martyrs and several injured as a result of the Israeli bombing of Jenin refugee camp," the Ramallah-based ministry said in a statement.
The Israeli military did not offer details but said it had carried out "an attack in the Jenin area".
The Palestinian ministry said among those killed was 15-year-old Mahmud Ashraf Mustafa Gharbiya.
Palestinian security forces of the Ramallah-based Palestinian Authority (PA) slammed the raid by the Israeli military.
"The pre-planned intervention ... thwarts all efforts being made to maintain security and order and restore life to normal," said Anwar Rajab, spokesman for the Palestinian forces, in a statement.
"It reflects the occupation's premeditated intentions to disrupt every national endeavour aimed at protecting our people."
Israeli forces make frequent raids on Palestinian towns and villages in the West Bank, which Israel has occupied since 1967.
Violence in the territory has soared since the war in Gaza broke out on October 7, 2023.
Israeli troops or settlers have killed at least 831 Palestinians in the West Bank since the start of the Gaza war, according to the health ministry.
At least 28 Israelis have been killed in Palestinian attacks or during Israeli military raids in the territory over the same period, according to Israeli official figures.
In recent weeks Jenin has also seen intra-Palestinian violence, with PA forces clashing with militants.
The clashes broke out amid a major PA raid on the Jenin camp after the December 5 arrest of a Jenin Battalion commander on charges of possessing weapons and illicit funds.
Armed factions in Jenin and elsewhere see themselves as offering more effective resistance to the Israeli occupation than the PA, which coordinates security matters with Israel.
Gaza rescuers say Israeli strikes kill 18
Gaza Strip, Palestinian Territories (AFP) Jan 14, 2025 -
Gaza's civil defence agency said Israeli air strikes and shelling killed at least 18 people across the territory on Tuesday, including children, while the Israeli military said it was targeting Hamas operatives.
Agency spokesman Mahmud Bassal said the strikes primarily targeted Deir el-Balah, Gaza City and the Khan Yunis area.
The Israeli military told AFP that the air force conducted overnight "several strikes on Hamas terrorists who were involved in terror activities".
"Last night was harsh and bloody," Bassal told AFP, accusing Israel of conducting "dozens of air and artillery strikes across all areas of the Strip".
"Eighteen people were killed and dozens injured" in strikes on a tent and several homes in Deir el-Balah, Khan Yunis and Gaza City, he added.
Ten people, including a one-year-old girl, were killed when a strike hit the home of the Abed family in the Al-Manara area of Khan Yunis, Bassal said.
The other deceased included the child's parents, grandfather and uncle, he added.
In a separate strike, four children were killed when a home belonging to the Abu al-Shaar family in the Al-Daraj neighbourhood of Gaza City was struck, Bassal said.
Another strike hit a tent filled with displaced Palestinians, killing three people in the Deir el-Balah area, he added.
Witnesses said an Apache helicopter fired on areas of Jabalia in northern Gaza, where Israeli forces have been conducting a sweeping offensive since October.
The latest strikes occurred as a "final round" of talks to reach a ceasefire and hostage release deal was due to begin in Qatar, according to a source briefed on the negotiations.
The war in Gaza began on October 7, 2023, when Hamas launched the deadliest attack in Israeli history.
The attack resulted in the deaths of 1,210 people, mostly civilians, according to an AFP tally of official Israeli figures.
Israel's retaliatory campaign in Gaza has killed 46,584 people, a majority of them civilians, according to the health ministry in the Hamas-run territory, figures that the UN considers reliable.
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