The following is a selection of reactions from around the globe to Trump's biggest foreign policy move since taking office:

- 'Psychological warfare' -

"This decision was an act of psychological warfare against Iran."

-- Iranian President Hassan Rouhani

- Uranium enrichment to resume? -

"I have instructed the Iranian Atomic Energy Organization to take the necessary measures for future actions so that, if necessary, we can resume industrial enrichment without limit."

-- Rouhani

- Stay the course -

"Stay true to your commitments as we will stay true to ours and together with the rest of the international community, we will preserve this nuclear deal."

-- European Union diplomatic chief Federica Mogherini

- 'Regret' -

"France, Germany and the UK regret the US decision to leave the JCPOA. The nuclear non-proliferation regime is at stake. We will work collectively on a broader framework, covering nuclear activity, the post-2025 period, ballistic activity and stability in the Middle East, notably Syria, Yemen and Iraq."

-- French President Emmanuel Macron, on Twitter, referring to the Iran deal by its formal name, the Joint Comprehensive Plan of Action

- Compliance -

"I call on other JCPOA participants to abide fully by their respective commitments under the JCPOA and on all other member-states to support this agreement."

-- United Nations Secretary-General Antonio Guterres

- 'Bold decision' -

"Israel fully supports President Trump's bold decision today to reject the disastrous nuclear deal with the terrorist regime in Tehran."

-- Israeli Prime Minister Benjamin Netanyahu

- Support from Saudi -

"The kingdom supports and welcomes the steps announced by the US president toward withdrawing from the nuclear deal... and reinstating economic sanctions against Iran."

--Saudi Arabia's foreign ministry

- 'Misguided' -

"The reality is clear. The JCPOA is working... That is why today's announcement is so misguided... I believe that the decision to put the JCPOA at risk without any Iranian violation of the deal is a serious mistake."

-- former US president Barack Obama, whose administration brokered the 2015 deal