Israeli strikes have targeted the Jabalia refugee camp twice in two days, killing and wounding dozens, according to the health ministry in the Hamas-run Palestinian territory.

Israel said Tuesday's raid was a successful hit on top Hamas commander Ibrahim Biari.

"Given the high number of civilian casualties & the scale of destruction following Israeli air strikes on Jabalia refugee camp, we have serious concerns that these are disproportionate attacks that could amount to war crimes," the office wrote on X, formerly Twitter.

Israel has relentlessly pounded Gaza in retribution for the worst attack in the country's history.

Hamas gunmen stormed across the border from Gaza on October 7, killing 1,400 people, mostly civilians, and taking more than 230 hostages, according to Israeli officials.

Israel's retaliatory bombing campaign has killed 8,796 people, mainly women and children, according to Hamas-run Gaza's health ministry.

AFPTV images from Wednesday's strike on the camp showed extensive damage and rescuers clawing through rubble to extract blood-stained casualties.

The large death toll from the strikes has drawn a chorus of international condemnation, with Bolivia severing diplomatic ties with Israel in protest.

Jordan recalled its ambassador to Israel "to condemn the Israeli war that is killing innocent people in Gaza".

UN chief Antonio Guterres is "appalled over the escalating violence in Gaza, including the killing of Palestinians, including women and children in Israeli air strikes in residential areas of the densely populated Jabalia refugee camp", his spokesman Stephane Dujarric said on Wednesday.

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